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Article

Fertilization-Induced Autophagy in Mouse Embryos is Independent of mTORC11

23 May 2014

Abstract excerpt

Autophagy is a dynamically regulated intracellular degradation system that is important for cellular processes such as amino acid production during starvation and intracellular quality control. Previously, we reported that autophagy is suppressed in oocytes but is rapidly up-regulated after fertilization. During this period, autophagy is thought to be important for the generation of amino acids from the bulk...

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PMID: 24855105
DOI: 10.1095/biolreprod.113.115816

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