Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CDK1, the Other ‘Master Regulator’ of Autophagy

30 Nov 2020

Abstract excerpt

Autophagy and cap-dependent mRNA translation are tightly regulated by the mechanistic target of rapamycin complex 1 (mTORC1) signalling complex in response to nutrient availability. However, the regulation of these processes, and mTORC1 itself, is different during mitosis, and this has remained an area of significant controversy; for example, studies have argued that autophagy is either repressed or highly active...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Epigenetics and DNA Methylation
Share to Genetics and Neurodevelopmental Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33272830
DOI: 10.1016/j.tcb.2020.11.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CDK1, the Other ‘Master Regulator’ of AutophagyPMID 33272830Read ↗

An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during MitosisSemantic proximity Read ↗

The Intricate Interplay between Cell Cycle Regulators and Autophagy in CancerSemantic proximity Read ↗

Autophagy Regulation by the Translation Machinery and Its Implications in CancerSemantic proximity Read ↗

The Role of Autophagy in Genome Stability through Suppression of Abnormal Mitosis under StarvationSemantic proximity Read ↗

So Many Roads: the Multifaceted Regulation of Autophagy InductionSemantic proximity Read ↗

mTORC1 activity oscillates throughout the cell cycle, promoting mitotic entry and differentially influencing autophagy inductionSemantic proximity Read ↗

The Role of Chaperone-Mediated Autophagy in Cell Cycle Control and Its Implications in CancerSemantic proximity Read ↗

A cyclin-dependent kinase, CDK11/p58, represses cap-dependent translation during mitosisSemantic proximity Read ↗

Autophagic flux is highly active in early mitosis and differentially regulated throughout the cell cycleSemantic proximity Read ↗

Autophagy and microtubules – new story, old playersSemantic proximity Read ↗

Kaposi’s Sarcoma-Associated Herpesvirus Lytic Replication Interferes with mTORC1 Regulation of Autophagy and Viral Protein SynthesisSemantic proximity Read ↗

Transcriptional regulation of mammalian autophagy at a glanceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.