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Article

Modulation of autophagy influences development and apoptosis in mouse embryos developing in vitro

17 May 2011

Abstract excerpt

Autophagyis, the bulk degradation of proteins and organelles, is essential for cellular maintenance, cell viability, and development, and is often involved in type II programmed cell death in mammals. This study investigated the expression levels of autophagy-related genes and the effect of 3-methyladenine (3-MA, an autophagy inhibitor) or rapamycin (an autophagy inducer) on the in vitro development and apoptosis...

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PMID: 21681844
DOI: 10.1002/mrd.21331

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