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Rapamycin treatment duringin vitromaturation of oocytes improves embryonic development after parthenogenesis and somatic cell nuclear transfer in pigs

1 Jan 2015

Abstract excerpt

This study was conducted to investigate the effects of rapamycin treatment during in vitro maturation (IVM) on oocyte maturation and embryonic development after parthenogenetic activation (PA) and somatic cell nuclear transfer (SCNT) in pigs. Morphologically good (MGCOCs) and poor oocytes (MPCOCs) were untreated or treated with 1 nM rapamycin during 0-22 h, 22-42 h, or 0-42 h of IVM. Rapamycin had no significant...

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PMID: 25797293
DOI: 10.4142/jvs.2015.16.3.373

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