Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rapid and cost effective screening of breast and ovarian cancer genes using novel sequence capture method in clinical samples.

Familial cancer - 1 Dec 2014

Arvai Kristóf, Horváth Péter, Balla Bernadett, Tőkés Anna M, Tobiás Bálint, Takács István, Nagy Zsolt, Lakatos Péter, Kósa János P

Abstract excerpt

BRCA1 and BRCA2 are two well-known genes in the background of hereditary breast and ovarian cancer. There is also evidence that several other genes play an important role in the pathogenesis of these two malignancies. Latest population-scaled studies showed that certain mutations in different genes could cause similar risk elevation like BRCA2 mutations. In this study we present a new method to analyse the risk...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Early Detection of Cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to BRCA2 gene

Share to Genetic Predisposition to Disease

Share to Genetic Testing

Share to High-Throughput Nucleotide Sequencing

Share to Oligonucleotide Array Sequence Analysis

Share to Ovarian Neoplasms

Source

Identifiers

PMID: 24853695
DOI: 10.1007/s10689-014-9730-7

Genes

BRCA2
BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rapid and cost effective screening of breast and ovarian cancer genes using novel sequence capture method in clinical samples.PMID 24853695Read ↗

Detection of inherited mutations for breast and ovarian cancer using genomic capture and massively parallel sequencing.Semantic proximity Read ↗

Rapid and cost-effective high-throughput sequencing for identification of germline mutations of BRCA1 and BRCA2.Semantic proximity Read ↗

Next-generation sequencing for the diagnosis of hereditary breast and ovarian cancer using genomic capture targeting multiple candidate genes.Semantic proximity Read ↗

HBOC multi-gene panel testing: comparison of two sequencing centers.Semantic proximity Read ↗

A new rapid methodological strategy to assess BRCA mutational status.Semantic proximity Read ↗

Rapid screening test of most frequent BRCA1/BRCA2 pathogenic variants in the NGS era.Semantic proximity Read ↗

Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing.Semantic proximity Read ↗

Detection of Germline Mutation in Hereditary Breast and/or Ovarian Cancers by Next-Generation Sequencing on a Four-Gene Panel.Semantic proximity Read ↗

Accurate detection of subclonal single nucleotide variants in whole genome amplified and pooled cancer samples using HaloPlex target enrichment.Semantic proximity Read ↗

Identification of the most common BRCA alterations through analysis of germline mutation databases: Is droplet digital PCR an additional strategy for the assessment of such alterations in breast and ovarian cancer families?Semantic proximity Read ↗

Screening of 1331 Danish breast and/or ovarian cancer families identified 40 novel BRCA1 and BRCA2 mutations.Semantic proximity Read ↗

Next-generation sequencing meets genetic diagnostics: development of a comprehensive workflow for the analysis of BRCA1 and BRCA2 genes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.