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Article

Death-associated protein kinase 1 has a critical role in aberrant tau protein regulation and function.

Cell death & disease - 22 May 2014

Kim B M, You M-H, Chen C-H, Lee S, Hong Y, Hong Y, Kimchi A, Zhou X Z, Lee T H

Abstract excerpt

The presence of tangles composed of phosphorylated tau is one of the neuropathological hallmarks of Alzheimer's disease (AD). Tau, a microtubule (MT)-associated protein, accumulates in AD potentially as a result of posttranslational modifications, such as hyperphosphorylation and conformational changes. However, it has not been fully understood how tau accumulation and phosphorylation are deregulated. In the...

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Identifiers

PMID: 24853415
DOI: 10.1038/cddis.2014.216
PMCID: PMC4047864

Genes

DAPK1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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