Article
Tagging SNPs in the MTHFR gene and risk of ischemic stroke in a Chinese population.
International journal of molecular sciences - 20 May 2014
Zhou Bao-Sheng, Bu Guo-Yun, Li Mu, Chang Bin-Ge, Zhou Yi-Pin
Abstract excerpt
Stroke is currently the leading cause of functional impairments worldwide. Folate supplementation is inversely associated with risk of ischemic stroke. Methylenetetrahydrofolate reductase (MTHFR) is an important enzyme involved in folate metabolism. The aim of this study is to examine whether genetic variants in MTHFR gene are associated with the risk of ischemic stroke and fasting total serum homocysteine (tHcy)...
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