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Article

Association between methylene tetrahydrofolate reductase polymorphisms and risk of ischemic stroke.

The International journal of neuroscience - 1 Jan 2021

Mazdeh Mehrdokht, Khazaie Mojtaba, Omrani Mir Davood, Noroozi Rezvan, Komaki Alireza, Karimi Masoud, Taheri Mohammad, Ghafouri-Fard Soudeh

Abstract excerpt

Background: The methylene tetrahydrofolate reductase (MTHFR) is a folate-dependent enzyme which catalyzes the conversion of homocysteine to methionine. Two single nucleotide polymorphisms (SNPs) within this gene namely rs1801133 (C677T) and rs1801131 (A1298C) have been associated with elevated risk of ischemic stroke and total serum homocysteine in some populations.Aim: To assess associations between MTHFR SNPs...

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Identifiers

PMID: 32098547
DOI: 10.1080/00207454.2020.1733554

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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