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Article

Genetic determinants of P wave duration and PR segment.

Circulation. Cardiovascular genetics - 1 Aug 2014

Verweij Niek, Mateo Leach Irene, van den Boogaard Malou, van Veldhuisen Dirk J, Christoffels Vincent M, Hillege Hans L, van Gilst Wiek H, Barnett Phil, de Boer Rudolf A, van der Harst Pim

Abstract excerpt

BACKGROUND: The PR interval on the ECG reflects atrial depolarization and atrioventricular nodal delay which can be partially differentiated by P wave duration and PR segment, respectively. Genome-wide association studies have identified several genetic loci for PR interval, but it remains to be determined whether this is driven by P wave duration, PR segment, or both. METHODS AND RESULTS: We replicated 7 of the...

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Identifiers

PMID: 24850809
DOI: 10.1161/CIRCGENETICS.113.000373
PMCID: PMC4141024

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FADS2
KCND3

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