Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of three novel genetic variations associated with electrocardiographic traits (QRS duration and PR interval) in East Asians.

Human molecular genetics - 15 Dec 2014

Hong Kyung-Won, Lim Ji Eun, Kim Jong Wook, Tabara Yasuharu, Ueshima Hirotsugu, Miki Tetsuro, Matsuda Fumihiko, Cho Yoon Shin, Kim Yeonjung, Oh Bermseok

Abstract excerpt

The electrocardiogram has several advantages in detecting cardiac arrhythmia-it is readily available, noninvasive and cost-efficient. Recent genome-wide association studies have identified single-nucleotide polymorphisms that are associated with electrocardiogram measures. We performed a genome-wide association study using Korea Association Resource data for the discovery phase (Phase 1, n = 6805) and two...

Topics

Join the communities discussing this publication.

Arrhythmias, Cardiac
Asian People
DNA-Binding Proteins
Electrocardiography
Muscle Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Quantitative Trait Loci

Sodium-Calcium Exchanger

Transcription Factors

Source

Identifiers

PMID: 25035420
DOI: 10.1093/hmg/ddu374

Genes

PRDM16
PRDM6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of three novel genetic variations associated with electrocardiographic traits (QRS duration and PR interval) in East Asians.PMID 25035420Read ↗

Genetic determinants of P wave duration and PR segment.Semantic proximity Read ↗

Fine-mapping, novel loci identification, and SNP association transferability in a genome-wide association study of QRS duration in African Americans.Semantic proximity Read ↗

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction.Semantic proximity Read ↗

Genome-wide association study of electrocardiographic parameters identifies a new association for PR interval and confirms previously reported associations.Semantic proximity Read ↗

Several common variants modulate heart rate, PR interval and QRS duration.Semantic proximity Read ↗

Genome- and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk.Semantic proximity Read ↗

Cardiac-specific inactivation of Prdm16 effects cardiac conduction abnormalities and cardiomyopathy-associated phenotypes.Semantic proximity Read ↗

Genome-wide association studies of the PR interval in African Americans.Semantic proximity Read ↗

Sequence variants with large effects on cardiac electrophysiology and disease.Semantic proximity Read ↗

GWAS of QRS Duration Identifies New Loci Specific to Hispanic/Latino Populations Swenson Hispanic/Latino QRS GWASSemantic proximity Read ↗

Fifteen Genetic Loci Associated With the Electrocardiographic P Wave.Semantic proximity Read ↗

GWAS of QRS duration identifies new loci specific to Hispanic/Latino populationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.