Article
Characterization of a nickel resistant mouse cell line.
Biological trace element research - 1 Jan 2000
Imbra R J, Wang X W, Costa M
Abstract excerpt
Nickel is a potent carcinogen and, at high concentrations, is toxic to mammalian cells. The effects associated with nickel exposure are well-documented but its mechanism of action in the cell has not yet been fully described. In order to understand the metabolic fate of nickel in mammalian cells,...
Topics
- Animals
- Cell Line
- Cell Survival
- Chromosomes
- DNA
- Drug Resistance
- Electrophoresis, Polyacrylamide Gel
- Gene Expression
- Mice
- Mice, Inbred BALB C
- Nickel
- Phenotype
- Staining and Labeling