Article
Uptake of cadmium is diminished in transfected mouse NIH/3T3 cells enriched for metallothionein.
The Journal of biological chemistry - 15 Feb 1992
Morton K A, Jones B J, Sohn M H, Schaefer A E, Phelps R C, Datz F L, Lynch R E
Abstract excerpt
To determine the relationship between cellular uptake of cadmium and content of metallothionein, we measured uptake of 109Cd in cells that differed in content of metallothionein (MT). MT cells were derived from NIH/3T3 cells by transfection with a plasmid containing the genome of bovine papilloma...
Topics
- 3T3 Cells
- Animals
- Biological Transport
- Bovine papillomavirus 1
- Cadmium
- Carrier Proteins
- Cell Survival
- Chromosome Deletion
- Cysteine
- Endoplasmic Reticulum Chaperone BiP
- Genetic Vectors
- Heat-Shock Proteins
- Metallothionein
- Mice
- Molecular Chaperones
- Phenotype
- Plasmids
- Promoter Regions, Genetic