Article
Integrated analysis using methylation and gene expression microarrays reveals PDE4C as a prognostic biomarker in human glioma.
Oncology reports - 1 Jul 2014
Bao Zhaoshi, Feng Ying, Wang Hongjun, Zhang Chuanbao, Sun Lihua, Yan Zhuohong, Liu Qingyang, Guo Tianzhu, Li Mingyang, Yang Xue, Jiang Chuanlu, Zhang Quangeng, Jiang Tao
Abstract excerpt
Hypermethylation of tumor suppressor promoters is generally accepted to indicate poor prognosis in glioma; however, the DNA methylation patterns associated with different glioma prognoses remain to be elucidated. In the present study, promoter methylation and gene expression microarrays were used to screen candidate genes between different grades of glioma. Survival analysis was performed using the Kaplan‑Meier...
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