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Article

Regulation and roles of Cdc7 kinase under replication stress

19 May 2014

Abstract excerpt

Cdc7 (cell division cycle 7) kinase together with its activation subunit ASK (also known as Dbf4) play pivotal roles in DNA replication and contribute also to other aspects of DNA metabolism such as DNA repair and recombination. While the biological significance of Cdc7 is widely appreciated, the molecular mechanisms through which Cdc7 kinase regulates these various DNA transactions remain largely obscure,...

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PMID: 24841992
DOI: 10.4161/cc.29251

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