Clinicopathological characteristics and genomic profiling in patients with transformed lymphoma: a monocentric retrospective study.

doi:10.1080/07853890.2024.2419556

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Article

Clinicopathological characteristics and genomic profiling in patients with transformed lymphoma: a monocentric retrospective study.

Annals of medicine - 1 Dec 2024

Zhao Xia, Bian Haiyan, Hao Fengyun, Shao Shihong, Wu Chuanhong, Zhang Qian, Wu Mingxuan, Li Zhiqiang, Gao Chengwen

Abstract excerpt

BACKGROUND: Transformed lymphoma occurs when indolent lymphoma transforms into more aggressive lymphoma usually associated with poor prognosis. METHODS: In this study, we analysed the immunophenotypes, prognostic factors and outcomes of 35 patients with transformed lymphoma from among 306 marginal zone lymphoma (MZL), 544 follicular lymphoma (FL) and 871 chronic lymphocytic leukaemia/small lymphocytic lymphoma...

Topics

Humans
Male
Female
Middle Aged
Aged
Retrospective Studies
Leukemia, Lymphocytic, Chronic, B-Cell
Adult
Lymphoma, Follicular
Mutation
Prognosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lymphoma, B-Cell, Marginal Zone

Exome Sequencing

Aged, 80 and over

Cell Transformation, Neoplastic

Lymphoma, Large B-Cell, Diffuse

Kaplan-Meier Estimate

Source

Open in PubMed Open full text

Identifiers

PMID: 39460552
DOI: 10.1080/07853890.2024.2419556
PMCID: PMC11514389

Genes

BCL10
CARD11
CD79B
CREBBP
EP300
MYD88
TNFAIP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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