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Article

CaMKII is essential for the cellular clock and coupling between morning and evening behavioral rhythms.

Genes & development - 15 May 2014

Kon Naohiro, Yoshikawa Tomoko, Honma Sato, Yamagata Yoko, Yoshitane Hikari, Shimizu Kimiko, Sugiyama Yasunori, Hara Chihiro, Kameshita Isamu, Honma Ken-ichi, Fukada Yoshitaka

Abstract excerpt

Daily behavioral rhythms in mammals are governed by the central circadian clock, located in the suprachiasmatic nucleus (SCN). The behavioral rhythms persist even in constant darkness, with a stable activity time due to coupling between two oscillators that determine the morning and evening activities. Accumulating evidence supports a prerequisite role for Ca(2+) in the robust oscillation of the SCN, yet the...

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Identifiers

PMID: 24831701
DOI: 10.1101/gad.237511.114
PMCID: PMC4035538

Genes

BMAL1
CLOCK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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