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Article

Does tautomerization of FapyG influence its mutagenicity?

Chemphyschem : a European journal of chemical physics and physical chemistry - 23 Jun 2014

Jena Nihar R, Mark Alan E, Mishra Phool C

Abstract excerpt

Oxidative degradation of guanine to 2,6-diamino-4-oxo-5-formamidopyrimidine (FapyG) is believed to be mutagenic. It has been proposed recently that the enol tautomer of FapyG is mainly responsible for this effect leading to a guanine-to-thymine mutation (T. H. Gehrke, U. Lischke, K. L. Gasteiger, S. Schneider, S. Arnold, H. C. Muller, D. S. Stephenson, H. Zipse, T. Carell, Nat. Chem. Biol.- 2013, 9, 455-461)....

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Identifiers

PMID: 24829167
DOI: 10.1002/cphc.201400045

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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