Article
Electric-field induced mutation of DNA: a theoretical investigation of the GC base pair.
Physical chemistry chemical physics : PCCP - 7 Apr 2013
Cerón-Carrasco José P, Jacquemin Denis
Abstract excerpt
It is known that intense external electric fields affect the proton transfer (PT) reactions in simple chemical systems, such as hydrated chlorhydric acid or formic acid dimer. Accordingly, electric fields might be used to modulate the PT reactions responsible for the spontaneous mutation mechanism in DNA. In this contribution, we investigate the effect of these fields on the tautomeric equilibria of the...
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