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Article

Urokinase gene 3'-UTR T/C polymorphism is associated with malignancy and ESRD in idiopathic membranous nephropathy.

BioMed research international - 1 Jan 2014

Chen Cheng-Hsu, Chen Shih-Yin, Shu Kuo-Hsiung, Wen Mei-Chin, Cheng Chi-Hung, Wu Ming-Ju, Yu Tung-Min, Chuang Ya-Wen, Tsai Fuu-Jen

Abstract excerpt

Idiopathic membranous nephropathy (MN) is one of the most common causes of nephrotic syndrome in adults, and 25% of MN patients proceed to ESRD. Urokinase plasminogen activator (uPA) may play an important role in reducing renal fibrosis. This study was conducted to clarify the relationship between uPA gene polymorphisms and clinical manifestations of MN. We recruited 91 biopsy-diagnosed MN patients and 105...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glomerulonephritis, Membranous

Share to Kaplan-Meier Estimate

Share to Kidney Failure, Chronic

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Share to Polymorphism, Single Nucleotide

Share to Urokinase-Type Plasminogen Activator

Source

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Identifiers

PMID: 24822208
DOI: 10.1155/2014/425095
PMCID: PMC4009112

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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