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Article

Association between genetic polymorphisms of the NPHS1 gene and membranous glomerulonephritis in the Taiwanese population.

Clinica chimica acta; international journal of clinical chemistry - 2 May 2010

Lo Wan-Yu, Chen Shih-Yin, Wang Huang-Joe, Shih Hung-Chang, Chen Cheng-Hsu, Tsai Chang-Hai, Tsai Fuu-Jen

Abstract excerpt

BACKGROUND: Membranous glomerulonephritis (MGN) is one of the most common causes of nephrotic syndrome in adults. NPHS1 encoding nephrin is a transmembrane protein of the immunoglobulin family. We clarified the relationship between NPHS1 gene polymorphisms and the susceptibility or progression of MGN. METHODS: We recruited a cohort of 132 biopsy-diagnosed MGN patients and 257 healthy subjects. Genotyping of three...

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Identifiers

PMID: 20138859
DOI: 10.1016/j.cca.2010.02.004

Genes

NPHS1

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