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Article

Impact of plasminogen activator inhibitor-1 gene polymorphisms on primary membranous nephropathy.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Oct 2008

Chen Cheng-Hsu, Shu Kuo-Hsiung, Wen Mei-Chin, Chen Kuo-Jung, Cheng Chi-Hung, Lian Jong-Da, Wu Ming-Ju, Yu Tung-Min, Tsai Fuu-Jen

Abstract excerpt

BACKGROUND: Idiopathic membranous nephropathy (MN) is one of the most common causes of nephrotic syndrome in adults, and 25% of MN patients proceed to end-stage renal disease. Plasminogen activator inhibitor type 1 (PAI-1) activity plays an important role in renal fibrosis. The objective of this study was to clarify the relationship between PAI-1 gene polymorphisms and the progression of MN-associated...

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Identifiers

PMID: 18495745
DOI: 10.1093/ndt/gfn258

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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