Article
Genetic association between membranous nephropathy and malignancies: a two-sample Mendelian randomisation study.
International urology and nephrology - 1 Jun 2024
Alemasi Akehu, Gu Lijiang, Zhou Yilun
Abstract excerpt
BACKGROUND: Various studies have reported that individuals with membranous nephropathy (MN) exhibit an elevated susceptibility to cancers. However, a causal relationship has not been clearly established. METHODS: We constructed a genetic score that predicts MN by utilizing genetic variants linked to this condition as instrumental variables. These genetic scores were then compared with lung, colon, breast, and...
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