Article

RNA sequencing identifies human placental<i>IL3RA</i>as a potential predictor of adverse cardiovascular outcomes in patients with severe preeclampsia

2023-06-19

Abstract excerpt

<h4>Background</h4> Mortality from preeclampsia (PE) and PE-associated morbidities are 3-to 5-fold higher in persons of African ancestry than in those of Asian and European ancestries. The placenta is central to the etiology of PE. However, how and to what extent the placenta contributes to worse PE outcomes in persons of African ancestry is yet to be fully elucidated. <h4>Objective</h4> We aimed to identify molec...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f68ed0d1-5290-5abf-b06a-0bdecd7d3a23
DOI: 10.1101/2023.06.16.23291528

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

RNA sequencing identifies human placental<i>IL3RA</i>as a potential predictor of adverse cardiovascular outcomes in patients with severe preeclampsiaDOI 10.1101/2023.06.16.23291528Read

Genomic Insights at the Maternal-Fetal Interface: Preeclampsia Subtypes and Clinical Implications.Semantic proximity Read

Molecular subtyping of hypertensive disorders of pregnancySemantic proximity Read

Human placental bed transcriptomic profiling reveals inflammatory activation of endothelial cells in preeclampsiaSemantic proximity Read

A Review of Candidate Genes and Pathways in Preeclampsia–An Integrated Bioinformatical AnalysisSemantic proximity Read

Overlapping Pathogenic Signalling Pathways and Biomarkers in Preeclampsia and Cardiovascular DiseaseSemantic proximity Read

Characterizing immune variation and diagnostic indicators of preeclampsia by single-cell RNA sequencing and machine learningSemantic proximity Read

Distinct molecular processes in placentae involved in two major subtypes of preeclampsiaSemantic proximity Read

Preeclampsia, Natural History, Genes, and miRNAs Associated with the SyndromeSemantic proximity Read

Preeclampsia Genomic Susceptibility Factors in Populations of African Ancestry: A Systematic Review and Meta-Analysis.Semantic proximity Read

Differences and similarities in the transcriptional profile of peripheral whole blood in early and late-onset preeclampsia: insights into the molecular basis of the phenotype of preeclampsiaa.Semantic proximity Read

Improved Prediction Accuracy for Late-Onset Preeclampsia Using cfRNA Profiles: A Comparative Study of Marker Selection StrategiesSemantic proximity Read

Placental whole transcriptome expression profile in patients with early-onset, late-onset preeclampsia and gestational diabetes mellitusSemantic proximity Read