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Article

Lower baseline performance but greater plasticity of working memory for carriers of the val allele of the COMT Val¹⁵⁸Met polymorphism.

Neuropsychology - 1 Mar 2015

Bellander Martin, Bäckman Lars, Liu Tian, Schjeide Brit-Maren M, Bertram Lars, Schmiedek Florian, Lindenberger Ulman, Lövdén Martin

Abstract excerpt

OBJECTIVE: Little is known about genetic contributions to individual differences in cognitive plasticity. Given that the neurotransmitter dopamine is critical for cognition and associated with cognitive plasticity, we investigated the effects of 3 polymorphisms of dopamine-related genes (LMX1A, DRD2, COMT) on baseline performance and plasticity of working memory (WM), perceptual speed, and reasoning. METHOD: One...

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Source

Identifiers

PMID: 24819065
DOI: 10.1037/neu0000088

Genes

COMT
DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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