Genetic variation in the TP53 pathway and bladder cancer risk. a comprehensive analysis.

doi:10.1371/journal.pone.0089952

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Article

Genetic variation in the TP53 pathway and bladder cancer risk. a comprehensive analysis.

PloS one - 1 Jan 2014

Pineda Silvia, Milne Roger L, Calle M Luz, Rothman Nathaniel, López de Maturana Evangelina, Herranz Jesús, Kogevinas Manolis, Chanock Stephen J, Tardón Adonina, Márquez Mirari, Guey Lin T, García-Closas Montserrat, Lloreta Josep, Baum Erin, González-Neira Anna, Carrato Alfredo, Navarro Arcadi, Silverman Debra T, Real Francisco X, Malats Núria

Abstract excerpt

INTRODUCTION: Germline variants in TP63 have been consistently associated with several tumors, including bladder cancer, indicating the importance of TP53 pathway in cancer genetic susceptibility. However, variants in other related genes, including TP53 rs1042522 (Arg72Pro), still present controversial results. We carried out an in depth assessment of associations between common germline variants in the TP53...

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Identifiers

PMID: 24818791
DOI: 10.1371/journal.pone.0089952
PMCID: PMC4018346

Genes

SERPINB5
BAK1
PMAIP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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