TP53 Arg72Pro Polymorphism and Pancreatic Cancer Susceptibility: Assessing rs1042522 as a Risk Factor for Pancreatic Cancer

Abstract excerpt

<h4>Background: </h4> Pancreatic cancer (PaC) is expected to become the 2nd leading cause of death by 2030 death in Western countries. There is a need to pinpoint high-risk populations since extensive screening would be economically impractical. <h4>Methods:</h4> This study has focused on the polymorphic variants of gene TP53 involved in pancreatic cancerogenesis by next generation sequencing. <h4>Results:</h4> Th...

Topics

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• Case-Control Studies
• CTLA-4 Antigen
• Genetic Predisposition to Disease
• Pancreatic Neoplasms
• Polymorphism, Single Nucleotide
• Receptors, Calcitriol
• Risk
• Tumor Suppressor Protein p53

Identifiers and source

Literature Corpus work

8f19c28f-5d73-522c-a2a2-bb33e0838200

DOI

10.20944/preprints202505.0412.v1