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Article

Common predisposition alleles for moderately common cancers: bladder cancer.

Current opinion in genetics & development - 1 Jun 2010

Kiltie Anne E

Abstract excerpt

Bladder cancer is the 5th commonest cancer and two major risk factors are smoking and occupational chemical exposure. There is also evidence of a genetic component to its aetiology. Candidate gene studies have mostly focused on genes involved in adduct metabolism and DNA repair, including a recent consortium-based meta-analysis. Recently, two genome-wide association studies in bladder cancer have been published...

Topics

Alleles
Genetic Predisposition to Disease
Genome-Wide Association Study
Genotype
Humans
Polymorphism, Single Nucleotide
Proto-Oncogene Proteins c-myc
Trans-Activators
Transcription Factors
Tumor Suppressor Proteins
Urinary Bladder Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20153630
DOI: 10.1016/j.gde.2010.01.002

Genes

MYC
PSCA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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