Article
Polymorphisms of TP53 are markers of bladder cancer vulnerability and prognosis.
Urologic oncology - 1 Oct 2013
Lin Hung-Yu, Yang Ming-Chang, Huang Chun-Hsiung, Wu Wen-Jen, Yu Tsan-Jung, Lung For-Wey
Abstract excerpt
OBJECTIVES: We have reported previously that the TP53 codon72 polymorphism (rs1042522) is associated with the incidence and invasiveness of bladder cancer in a Han Chinese population. Using an enlarged sample, we investigated the role of rs1042522 and of tagSNPs that were predicted to be in linkage disequilibrium with codon72 in relation to the incidence, invasiveness, and prognosis of bladder cancer. METHODS AND...
Topics
- Aged
- Asian People
- Base Sequence
- Female
- Gene Frequency
- Genetic Predisposition to Disease
