Article
CTLA4 genetic variants associated with urothelial bladder cancer susceptibility.
Urologic oncology - 1 Nov 2024
Koike Alexsandro, Colado Simão Andréa Name, Ahrens Tainah Mendes, Cardoso Kaue de Morais, Espinosa Beatriz Rabello, Gualberto Roberson Henrique Gobanhi, Santos Daniel Felipe Piva, Trigo Guilherme Lerner, Reiche Edna Maria Vissoci, Lozovoy Marcell Alysson Batisti
Abstract excerpt
PURPOSE: The study evaluated the relationship between the CTLA4 rs231775 (+49A>G) and rs231779 (+1822C>T) variants and susceptibility, stage, prognosis and response to treatment of the urothelial bladder cancer (UBC). METHODS: A total of 140 patients with UBC and 145 controls were enrolled. The patients were stratified as non-muscle invasive bladder cancer (NMIBC) and muscle invasive bladder cancer (MICB),...
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