Article
KISS1 receptor is preferentially expressed in clinically non-functioning pituitary tumors.
Pituitary - 1 Jun 2015
Yaron Marianna, Renner Ulrich, Gilad Suzan, Stalla Günter K, Stern Naftali, Greenman Yona
Abstract excerpt
OBJECTIVE: KISS1 is a metastasis suppressor gene involved in cancer biology. Given the high expression levels of KISS1 and KISS1R in the hypothalamus and the pituitary respectively, we hypothesized that this system could possibly affect tumor invasiveness and clinical behavior of pituitary tumors. METHODS: Expression levels of KISS1 and KISS1R mRNA were evaluated by RT-PCR. Clinical information pertaining tumor...
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