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Article

Molecular biology of the kisspeptin receptor: signaling, function, and mutations.

Advances in experimental medicine and biology - 1 Jan 2013

Bianco Suzy Drummond Carvalho, Kaiser Ursula B

Abstract excerpt

Kisspeptin receptor (KISS1R) signaling is essential for the hallmark increase in pulsatile GnRH secretion characteristic of the onset of puberty in humans and experimental animals. Loss-of-function mutations in KISS1R are associated with idiopathic hypogonadotropic hypogonadism in humans. Also, mutations with confirmed association with idiopathic central precocious puberty were identified in kisspeptin and...

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Source

Identifiers

PMID: 23550005
DOI: 10.1007/978-1-4614-6199-9_7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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