Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MicroRNA-21 Regulates hTERT via PTEN in Hypertrophic Scar Fibroblasts

9 May 2014

Abstract excerpt

BACKGROUND: As an important oncogenic miRNA, microRNA-21 (miR-21) is associated with various malignant diseases. However, the precise biological function of miR-21 and its molecular mechanism in hypertrophic scar fibroblast cells has not been fully elucidated. METHODOLOGY/PRINCIPAL FINDINGS: Quantitative Real-Time PCR (qRT-PCR) analysis revealed significant upregulation of miR-21 in hypertrophic scar fibroblast...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dermatologic Treatments and Research
Share to Hair Growth and Disorders
Share to melanin and skin pigmentation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24817011
DOI: 10.1371/journal.pone.0097114

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MicroRNA-21 Regulates hTERT via PTEN in Hypertrophic Scar FibroblastsPMID 24817011Read ↗

TGF-β1 promotes scar fibroblasts proliferation and transdifferentiation via up-regulating MicroRNA-21Semantic proximity Read ↗

MicroRNA-21 Affects Proliferation and Apoptosis by Regulating Expression of PTEN in Human Keloid FibroblastsSemantic proximity Read ↗

MiR-21-5p Links Epithelial-Mesenchymal Transition Phenotype with Stem-Like Cell Signatures via AKT Signaling in Keloid Keratinocytes.Semantic proximity Read ↗

Microrna-21: A Central Regulator of Fibrotic Diseases Via Various TargetsSemantic proximity Read ↗

miR-21 promotes human nucleus pulposus cell proliferation through PTEN/AKT signaling.Semantic proximity Read ↗

Pleiotropic microRNA-21 in pulmonary remodeling: novel insights for molecular mechanism and present advancementsSemantic proximity Read ↗

Inhibitory effect of microRNA-21 on pathways and mechanisms involved in cardiac fibrosis developmentSemantic proximity Read ↗

Identification of a Novel lincRNA-p21-miR-181b-PTEN Signaling Cascade in Liver FibrosisSemantic proximity Read ↗

A miRNA-21-Mediated PTEN/Akt/NF-κB Axis Promotes Chronic Obstructive Pulmonary Disease PathogenesisSemantic proximity Read ↗

MiR-21 Regulates Keloid Formation by Downregulating Smad7 via the TGF-β/Smad Signaling PathwaySemantic proximity Read ↗

MicroRNA-21 Overexpression Contributes to Vestibular Schwannoma Cell Proliferation and SurvivalSemantic proximity Read ↗

LncRNA PVT1 Promotes the Progress of Hypertrophic Scar via Regulating the Proliferation and Migration of Myofibroblasts Through Targeting miR-29a-3p/STAT3Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.