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PD-L1 gene polymorphisms and low serum level of PD-L1 protein are associated to type 1 diabetes in Chile.

Diabetes/metabolism research and reviews - 1 Nov 2014

Pizarro Carolina, García-Díaz Diego F, Codner Ethel, Salas-Pérez Francisca, Carrasco Elena, Pérez-Bravo Francisco

Abstract excerpt

INTRODUCTION: Type 1 diabetes (T1D) has a complex etiology in which genetic and environmental factors are involved, whose interactions have not yet been completely clarified. In this context, the role in PD-1 pathway and its ligands 1 and 2 (PD-L1 and PD-L2) have been proposed as candidates in several autoimmune diseases. The aim of this work was to determine the allele and haplotype frequency of six gene...

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PMID: 24816853
DOI: 10.1002/dmrr.2552

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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