Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PD-1 gene haplotype is associated with the development of type 1 diabetes mellitus in Japanese children.

Human genetics - 1 Apr 2007

Ni Ronghua, Ihara Kenji, Miyako Kenichi, Kuromaru Ryuichi, Inuo Mika, Kohno Hitoshi, Hara Toshiro

Abstract excerpt

Interaction between Programmed cell death-1 (PD-1), a member of costimulatory molecules, and its receptors Programmed cell Death-1 Ligand 1 (PD-L1) and Programmed cell Death-1 Ligand 2 (PD-L2), play an important role in the negative regulation of immune reactions. It was shown that a polymorphism in a regulatory site of the PD-1 gene was associated with susceptibility to several autoimmune diseases in various...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, CD
Share to Apoptosis Regulatory Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 1

Share to Infant

Share to Infant, Newborn

Share to Ligands

Share to Programmed Cell Death 1 Receptor

Source

Identifiers

PMID: 17203303
DOI: 10.1007/s00439-006-0309-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PD-1 gene haplotype is associated with the development of type 1 diabetes mellitus in Japanese children.PMID 17203303Read ↗

Association of a putative regulatory polymorphism in the PD-1 gene with susceptibility to type 1 diabetes.Semantic proximity Read ↗

Molecular scanning of the gene for programmed cell death-1 (PDCD-1) as a candidate for type 1 diabetes susceptibility.Semantic proximity Read ↗

Low programmed cell death-1 (PD-1) expression in peripheral CD4(+) T cells in Japanese patients with autoimmune type 1 diabetes.Semantic proximity Read ↗

Association of PD-1 gene polymorphisms and serum soluble PD-1 levels with type 1 diabetes mellitus susceptibility in a Chinese Han cohort: a case-control study.Semantic proximity Read ↗

Trinucleotide repeats of programmed cell death-1 gene are associated with susceptibility to type 1 diabetes mellitus.Semantic proximity Read ↗

Association of PD-1 and PD-L1 Genetic Polymorphyisms with Type 1 Diabetes SusceptibilitySemantic proximity Read ↗

Genetic susceptibility of childhood type 1 diabetes mellitus in Japan.Semantic proximity Read ↗

Effects of the programmed cell death 1 (PDCD1) polymorphisms in susceptibility to systemic lupus erythematosusSemantic proximity Read ↗

[Programmed cell death 1 (PDCD1) gene polymorphisms and type 1 diabetes in Chilean children].Semantic proximity Read ↗

Genetic susceptibility to type 1 diabetes mellitus in humans.Semantic proximity Read ↗

PD-L1 gene polymorphisms and low serum level of PD-L1 protein are associated to type 1 diabetes in Chile.Semantic proximity Read ↗

The Role of HLA Class II Two-Locus Haplotypes and Genotypes in Chinese With Type 1 Diabetes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.