Article
[Programmed cell death 1 (PDCD1) gene polymorphisms and type 1 diabetes in Chilean children].
Revista medica de Chile - 1 May 2010
Flores Sylvia, Beems Megan, Oyarzún Amaya, Carrasco Elena, Pérez Francisco
Abstract excerpt
BACKGROUND: Programmed cell death 1 (PDCD-1) immune-receptor is a key element in the negative regulation of peripheral tolerance in T cells. Several polymorphisms of this gene have been described and it is linked with susceptibility to autoimmune diseases like Lupus and Multiple Sclerosis. AIM: To analyze four gene polymorphisms of PDCD-1 gene and explore its possible contribution as a susceptibility gene for...
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