Article
Lack of association of the MDR1 C3435T polymorphism with susceptibility to gastric cancer and peptic ulcer: a systemic review and meta-analysis.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014
Wu Dan-Dan, Zhang Ji-Xiang, Li Jiao, Dong Wei-Guo
Abstract excerpt
BACKGROUND: The multidrug resistance 1 gene (MDR1) C3435T polymorphism has been demonstrated to influence the P-glycoprotein (P-gp) activity level which is related to inflammation and carcinogenesis. This meta-analysis was performed to estimate the association between the MDR1 C3435T polymorphism and the risk of gastric cancer (GC) and peptic ulcer (PU). MATERIALS AND METHODS: A literature search was conducted...
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