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Article

MDR1 C3435T polymorphism has no influence on developing Helicobacter pylori infection-related gastric cancer and peptic ulcer in Japanese.

Life sciences - 15 Aug 2008

Sugimoto Mitsushige, Furuta Takahisa, Shirai Naohito, Kodaira Chise, Nishino Masafumi, Yamade Mihoko, Ikuma Mutsuhiro, Sugimura Haruhiko, Ishizaki Takashi, Hishida Akira

Abstract excerpt

AIMS: P-glycoprotein, the gene product of multidrug-resistant transporter-1 (MDR1), confers multidrug resistance against antineoplastic agents but also affects the kinetic disposition of some drugs and carcinogens. MDR1 C3435T polymorphism influences the development of colon cancer and adult acute myeloid leukemia by the association with transporting carcinogen. The aim of this study was to clarify the...

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PMID: 18644389
DOI: 10.1016/j.lfs.2008.06.022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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MDR1 C3435T polymorphism has no influence on developing Helicobacter pylori infection-related gastric cancer and peptic ulcer in Japanese.PMID 18644389Read ↗

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