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Article

Differential inflammasome activation by Porphyromonas gingivalis and cholesterol crystals in human macrophages and coronary artery endothelial cells.

Atherosclerosis - 1 Jul 2014

Champaiboon Chantrakorn, Poolgesorn Mahatana, Wisitrasameewong Wichaya, Sa-Ard-Iam Noppadol, Rerkyen Pimprapa, Mahanonda Rangsini

Abstract excerpt

OBJECTIVE: Observational evidence suggests association between periodontitis and atherosclerotic vascular disease (ASVD), however the cause-effect remains unclear. In this study, we investigated the mechanistic link of the two diseases by measuring production of interleukin (IL)-1β, a potent inflammatory cytokine, induced via inflammasome activation by a key periodontal pathogen--Porphyromonas gingivalis LPS and...

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PMID: 24814648
DOI: 10.1016/j.atherosclerosis.2014.04.007

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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