Article
Modulation of inflammasome activity by <i>Porphyromonas gingivalis</i> in periodontitis and associated systemic diseases
1 Jan 2016
Abstract excerpt
Inflammasomes are large multiprotein complexes localized in the cytoplasm of the cell. They are responsible for the maturation of pro-inflammatory cytokines such as interleukin-1β (IL-1β) and IL-18 as well as for the activation of inflammatory cell death, the so-called pyroptosis. Inflammasomes assemble in response to cellular infection, cellular stress, or tissue damage; promote inflammatory responses and are of...
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