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Article

Dopamine-related genotypes and the dose-response effect of methylphenidate on eating in attention-deficit/hyperactivity disorder youths.

Journal of child and adolescent psychopharmacology - 1 Apr 2009

Leddy John J, Waxmonsky James G, Salis Robert J, Paluch Rocco A, Gnagy Elizabeth M, Mahaney Patrick, Erbe Richard, Pelham William E, Epstein Leonard H

Abstract excerpt

OBJECTIVE: There are individual differences in the effects of methylphenidate (MPH), a dopamine (DA) transport inhibitor, on appetite in children with attention-deficit/hyperactivity disorder (ADHD). One potential moderating factor is variation in brain DA activity, which is influenced by dopamine-related genes: the DA transporter (DAT) (SLC6A3), the DA D2 receptor (DRD2), and the DA D4 receptor (DRD4) genes. The...

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Source

Identifiers

PMID: 19364291
DOI: 10.1089/cap.2008.046

Genes

DRD2
DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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