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Article

The hinge region of type VII collagen is intrinsically disordered.

Matrix biology : journal of the International Society for Matrix Biology - 1 Jun 2014

Richer Barbara Christine, Seeger Karsten

Abstract excerpt

Type VII collagen (Col7) is important for skin integrity. As a major component of the anchoring fibrils, Col7 is essential for linking different skin layers together. The central collagenous domain of Col7 contains several interruptions of the collagen triple helix. The longest interruption is 39 amino acids long and referred to as the hinge region. The hinge region is highly conserved between species. This...

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Identifiers

PMID: 24810542
DOI: 10.1016/j.matbio.2014.04.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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