Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The vWFA2 domain of type VII collagen is responsible for collagen binding.

Biochemical and biophysical research communications - 11 Jan 2013

Wegener Henrik, Leineweber Sarah, Seeger Karsten

Abstract excerpt

Type VII collagen (Col7) is the major component of anchoring fibrils and very important for skin integrity. This is emphasized by the Col7 related skin blistering diseases dystrophic epidermolysis bullosa and epidermolysis bullosa acquisita. Structural data that provides insights into the interaction network of Col7 and thus providing a basis for a better understanding of the pathogenesis of the diseases is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Binding Sites
Share to Collagen Type I
Share to Collagen Type VII

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lysine

Share to Magnesium

Share to Protein Structure, Secondary

Share to Protein Structure, Tertiary

Share to von Willebrand Factor

Source

Identifiers

PMID: 23237810
DOI: 10.1016/j.bbrc.2012.11.119

Genes

SPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The vWFA2 domain of type VII collagen is responsible for collagen binding.PMID 23237810Read ↗

Type VII collagen: the anchoring fibril protein at fault in dystrophic epidermolysis bullosa.Semantic proximity Read ↗

Biology of anchoring fibrils: lessons from dystrophic epidermolysis bullosa.Semantic proximity Read ↗

The COL7A1 mutation database.Semantic proximity Read ↗

Type VII Collagen Disorders Simplified.Semantic proximity Read ↗

Epidermolysis Bullosa (EB) Acquisita in an Adult Patient with Previously Unrecognized Mild Dystrophic EB and Biallelic COL7A1 Mutations.Semantic proximity Read ↗

A structure of a collagen VI VWA domain displays N and C termini at opposite sides of the protein.Semantic proximity Read ↗

The hinge region of type VII collagen is intrinsically disordered.Semantic proximity Read ↗

Mapping structural landmarks, ligand binding sites, and missense mutations to the collagen IV heterotrimers predicts major functional domains, novel interactions, and variation in phenotypes in inherited diseases affecting basement membranes.Semantic proximity Read ↗

Single amino acid substitutions in procollagen VII affect early stages of assembly of anchoring fibrils.Semantic proximity Read ↗

Collagen VII plays a dual role in wound healingSemantic proximity Read ↗

Molecular basis for the dystrophic forms of epidermolysis bullosa: mutations in the type VII collagen gene.Semantic proximity Read ↗

[Dermis collagens: beyond their structural properties].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.