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Article

Single-nucleotide polymorphisms and activity analysis of the promoter and enhancer of the pig lactase gene.

Gene - 15 Jul 2014

Du Hai-Ting, Zhu Hong-Yan, Wang Jia-Mei, Zhao Wei, Tao Xiao-Li, Ba Cai-Feng, Tian Yu-Min, Su Yu-Hong

Abstract excerpt

Lactose intolerance in northern Europeans is strongly associated with a single-nucleotide polymorphism (SNP) located 14 kb upstream of the human lactase gene: -13,910 C/T. We examined whether SNPs in the 5' flanking region of the pig lactase gene are similar to those in the human gene and whether these polymorphisms play a functional role in regulating pig lactase gene expression. The 5' flanking region of the...

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Share to Enhancer Elements, Genetic
Share to Gene Expression Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

Share to Promoter Regions, Genetic

Share to Sus scrofa

Source

Identifiers

PMID: 24809963
DOI: 10.1016/j.gene.2014.05.007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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