Article
Linkage disequilibrium and functional analysis of PRE1 insertion together with SNPs in the promoter region of IGFBP7 gene in different pig breeds.
Journal of applied genetics - 1 May 2018
Wu Qingyan, Yu Hao, Wei Wenzhen, Cheng Yunyun, Huang Shan, Shi Hongyu, Liu Songcai, Xia Jichao, Jia Hongyao, Hao Linlin
Abstract excerpt
Polymorphisms in regions upstream of transcription initiation site may modify the transcriptional activity of target genes by changing promoter activity. This study aims to determine whether or not polymorphisms at porcine IGFBP7 promoter region affect gene expression. In this study, eight SNPs and one PRE1 insertion in this region were first confirmed. The PRE1 insertion was widespread in 20 Chinese indigenous...
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