Article
MET gene copy number gain is an independent poor prognostic marker in Korean stage I lung adenocarcinomas.
Annals of surgical oncology - 1 Feb 2014
Jin Yan, Sun Ping-Li, Kim Hyojin, Seo An Na, Jheon Sanghoon, Lee Choon-Taek, Chung Jin-Haeng
Abstract excerpt
BACKGROUND: MET gene copy number gain (CNG) and protein overexpression have been reported in lung cancer, but the clinical implications in early stage adenocarcinoma remain unclear. METHODS: We investigated MET gene copy number and protein expression in 141 cases of surgically resected stage I pulmonary adenocarcinoma. MET gene CNG was determined by silver in situ hybridization, and MET protein expression was...
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