Article
Renin-angiotensin-aldosterone system polymorphisms and 5-year mortality in survivors of acute myocardial infarction: a report from the Osaka Acute Coronary Insufficiency Study.
International heart journal - 1 Jan 2014
Hara Masahiko, Sakata Yasuhiko, Nakatani Daisaku, Suna Shinichiro, Usami Masaya, Matsumoto Sen, Sugitani Toshifumi, Ozaki Kouichi, Nishino Masami, Sato Hiroshi, Kitamura Tetsuhisa, Nanto Shinsuke, Hamasaki Toshimitsu, Tanaka Toshihiro, Hori Masatsugu, Komuro Issei
Abstract excerpt
This study sought to evaluate whether genetic variants in the renin-angiotensin-aldosterone system (RAAS) have an impact on long-term mortality after acute myocardial infarction (AMI) in the percutaneous coronary intervention (PCI) era. We investigated the impacts of individual and combinations of 4 major RAAS genetic variants, angiotensinogen (AGT) T1311C, angiotensin-converting enzyme (ACE) insertion/deletion...
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