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Article

Renin-angiotensin-aldosterone system gene polymorphisms and coronary artery disease: detection of gene-gene and gene-environment interactions.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2012

Jia En-Zhi, Xu Zhen-Xia, Guo Chang-Yan, Li Li, Gu Yan, Zhu Tie-Bing, Wang Lian-Sheng, Cao Ke-Jiang, Ma Wen-Zhu, Yang Zhi-Jian

Abstract excerpt

OBJECTIVE: The objective of this study was to explore the association between coronary artery disease and genetic polymorphisms of the renin-angiotensin-aldosterone system (RAAS) pathway. In addition, we examined the interactions between demographic and lifestyle risk factors (environmental factors including age, sex, smoking status, alcohol intake) and RAAS polymorphisms on disease risk. METHODS: A total of 1089...

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Source

Identifiers

PMID: 22508051
DOI: 10.1159/000338498

Genes

ACE
AGT
AGTR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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