Article
Relationship of renin-angiotensin-aldosterone system polymorphisms and phenotypes to mortality in Chinese coronary atherosclerosis patients.
Scientific reports - 11 Apr 2014
Jia En-Zhi, Chen Zhao-Hong, An Feng-Hui, Li Li-Hua, Li-Li, Guo Chang-Yan, Gu Yan, Liu Zhe, Li Zhao-Yang, Zhu Tie-Bing, Wang Lian-Sheng, Li Chun-Jian, Kong Xiang-Qing, Ma Wen-Zhu, Yang Zhi-Jian
Abstract excerpt
We performed a large, long-term cohort study to evaluate the association of renin-angiotensin-aldosterone system gene polymorphisms and baseline phenotypes to all-cause mortality among patients with angiographically confirmed coronary atherosclerosis. The study included 1075 subjects who underwent coronary angiography. Patients were genotyped for eight polymorphisms (rs4343, rs5186, rs5182, rs5049, rs5051, ,...