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Article

Genetic variation in the renin-angiotensin-aldosterone system is associated with cardiovascular risk factors and early mortality in established coronary heart disease.

Journal of human hypertension - 1 Apr 2013

Ellis K L, Palmer B R, Frampton C M, Troughton R W, Doughty R N, Whalley G A, Ellis C J, Pilbrow A P, Skelton L, Yandle T G, Richards A M, Cameron V A

Abstract excerpt

This study examined renin-angiotensin-aldosterone (RAAS) system gene variants for associations with cardiovascular risk factors and outcomes in coronary heart disease. Coronary disease patients (n=1186) were genotyped for 21 single-nucleotide polymorphisms (SNPs) within angiotensinogen (AGT), angiotensin-converting enzyme (ACE), angiotensin-II type-1 receptor (AGTR1) and aldosterone synthase (CYP11B2)....

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Source

Identifiers

PMID: 22739771
DOI: 10.1038/jhh.2012.24

Genes

AGT
ACE
AGTR1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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