Article
Synergistic effect of angiotensin II type-1 receptor 1166A/C with angiotensin-converting enzyme polymorphism on risk of acute myocardial infarction in north Indians.
Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Dec 2012
Kaur Rupinder, Das Reena, Ahluwalia Jasmina, Kumar Rohit Manoj, Talwar K K
Abstract excerpt
INTRODUCTION: This first study from north India investigated the synergistic effect of AT1R 1166A/C with the ACE I/D polymorphism on risk of acute myocardial infarction (AMI). MATERIALS AND METHODS: Traditional coronary risk factors, ACE I/D and AT1R 1166A/C polymorphism were analyzed in 350 patients with AMI and 350 matched controls. RESULTS: In univariate analysis, hypertension (52.9% vs. 11.1%; OR=8.9; 95%CI...
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